Users may change their drug of choice if your testing program isn't comprehensive enough. This is an expanded test for those of you who feel that you might need to test more thoroughly. This has a specific test for the detection of Oxycodone*. The 12 panel has all the screens of the 6 panel, plus it differentiates between meth and Ecstasy, and detects Methadone (the newest killer of teens), Barbiturates, PCP, and PPX (Darvocet). Now, with the rising popularity of Molly (pure MDMA), this all inclusive screen may well be worth the additional cost.